Nutrient composition

Age related macular degeneration (AMD) is the leading cause of severe visual loss in people aged over 50 in the developed world. Early AMD is characterised clinically by yellow deposits known as drusen and changes in pigmentation of the retina. Late AMD develops when there is an ingrowth...

Background Choline, an essential nutrient, is present in human milk and important for brain function. Adequate intakes (AIs) for choline were established by the IOM in 1998, but nationally representative estimates of intake are limited. Objective To assess intakes and sources of choline in...

Objective To estimate choline intakes of US subpopulations including children, men, women and pregnant women. Background Choline is an essential nutrient which plays critical roles in brain development and homocysteine metabolism. Choline is widely distributed in foods; good sources...

Lutein and zeaxanthin accumulate in the macular pigment of the retina, and are associated with a reduced incidence of macular degeneration. The objective of the study was to investigate the effect of consuming 1 egg/d for 5-wk on the serum concentrations of lutein, zeaxanthin, lipids and...

Choline is a required nutrient, and some humans deplete quickly when fed a low-choline diet, whereas others do not. Endogenous choline synthesis can spare some of the dietary requirement and requires one-carbon groups derived from folate metabolism. We examined whether major genetic...